Fmoc-PEG2-propionic acid
Fmoc-9-Amino-4,7-Dioxanonanoic acid
CAS: 872679-70-4
Molecular Formula: C22H25NO6
Fmoc-PEG2-propionic acid - Names and Identifiers
Fmoc-PEG2-propionic acid - Physico-chemical Properties
| Molecular Formula | C22H25NO6 |
| Molar Mass | 399.44 |
| Density | 1.243±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 95.0 to 99.0 °C |
| Boling Point | 621.0±50.0 °C(Predicted) |
| Solubility | soluble in Methanol |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 4.28±0.10(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Fmoc-PEG2-propionic acid - Reference Information
| biological activity | Fmoc-NH-PEG2-CH2CH2COOH is a degradable ADC linker used in antibody drug conjugate (ADC) synthesis. Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis. |
Last Update：2024-04-09 21:21:28
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View History
Fmoc-PEG2-propionic acid
25T7-NBOMe (hydrochloride) (CRM)
6-溴咪唑[1,2-A]嘧啶-2-甲酸乙酯
tetrahydrophthalic acid diglycidylester
SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS4-CYS9 )
2-丙烯酸-2-乙基己酯的均聚物
乙基 4-氟苯并[B]噻吩-2-羧酸酯
2-(3-溴-4-甲氧基苯基)乙酸
2-({3-[(3-PHENYLPROPANOYL)AMINO]ANILINO}CARBONYL)-BENZOIC ACID
(4-甲基异噁唑-3-基)甲胺
25T7-NBOMe (hydrochloride) (CRM)
6-溴咪唑[1,2-A]嘧啶-2-甲酸乙酯
tetrahydrophthalic acid diglycidylester
SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS4-CYS9 )
2-丙烯酸-2-乙基己酯的均聚物
乙基 4-氟苯并[B]噻吩-2-羧酸酯
2-(3-溴-4-甲氧基苯基)乙酸
2-({3-[(3-PHENYLPROPANOYL)AMINO]ANILINO}CARBONYL)-BENZOIC ACID
(4-甲基异噁唑-3-基)甲胺